Cotrimoxazole and Diaper Rash
Diaper candidiasis or diaper rash as it is famously known is a fungal (yeast) infections that usually affect babies who dressed in diapers. Treating this yeast infection has been proven to be effective with clotrimazole. Clotrimazole is classified under the anti-microbial class of antifungals. This drug achieves its therapeutic roles through inhibition of the process of the fungal cell membrane. To accomplish its effects specifically, clotrimazole inhibits the synthesis of the ergosterol component of the fungal cell membrane by interfering with the cytochrome p-450 enzyme necessary to catalyze the synthetic process (Akins & Sobel, 2017).